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Nitric oxide precursor in HoneyPezil: what arginine and citrulline prove

Quick answer

A nitric oxide precursor is a compound the body can turn into nitric oxide, and sellers describe arginine and citrulline that way. HoneyPezil holds at most 400 mg of arginine ingredients and 200 mg of citrulline ingredients per capsule. Studies used grams, and none we found tested memory at the label amounts.

  • FormatCapsules, 30 per bottle
  • Label serving1 capsule a day
  • Guarantee60-day money-back guarantee

Written by the HoneyPezil label deskUpdated · 4 min read

A gold drawing of a blood vessel
Brand artwork, not a result, not a customer.

Definition01

What is a nitric oxide precursor in HoneyPezil?

A nitric oxide precursor is an ingredient the body can use to make nitric oxide, a molecule involved in widening blood vessels.

In HoneyPezil, that label covers four of the seven lines: two arginine lines and two citrulline lines. The label itself does not use the words nitric oxide.

Per capsule, the label prints arginine (base) 200 mg and arginine AKG 200 mg, citrulline HCl 100 mg and citrulline malate 100 mg. The AKG and malate lines are not split, so the totals are at most 400 mg and at most 200 mg.

Studies02

What do studies of arginine and citrulline show?

Studies of arginine and citrulline use grams and look at blood vessels, blood pressure and exercise, not memory.

Oral citrulline raised blood arginine more than arginine itself at gram doses, yet no regimen improved a vessel-widening test in 20 healthy people (Schwedhelm 2008, Citrulline vs arginine in the body). In 24 active men, 12 g a day of an arginine AKG product for 7 days did not change blood flow measures against placebo (Willoughby 2011, AAKG 12 g a day and blood flow). Blood pressure analyses of citrulline disagree (Barkhidarian 2019, Citrulline and blood pressure) (Mirenayat 2018, Citrulline and blood pressure (no effect)).

Label amount and what was studied
LineLabelStudied
Arginine ingredientsAt most 400 mg4 g a day or more in blood pressure trials (Shiraseb 2022, Arginine and blood pressure)
Citrulline ingredientsAt most 200 mgUp to 6 g a day (NIH ODS, Exercise and athletic performance supplements)

The gap03

Does a nitric oxide precursor help memory?

We found no study showing that a nitric oxide precursor helps memory at the label amounts, so the link is unproven.

The bars set the label against a studied amount. They show a gap, not a verdict, because no study tested the label doses. The National Institute on Aging says no vitamin or supplement is currently recommended for preventing cognitive decline (NIA, Cognitive health and older adults).

One small trial in 19 older adults found arginine did not help a thinking test, and its authors said it worsened a small-vessel measure (Beckman 2018, Arginine and executive function in older adults). That was a single short trial, not proof of harm.

  • L-arginine: base + AKG, at most

    The label holds 27% of the low study amount
    Per capsule on the HoneyPezil label400 mg
    1,500 mg a day: arginine silicate (a different compound) in a company-funded mental-test study1,500 mg

    Both bars use one scale. The label amount is printed on the Supplement Facts panel. (Kalman 2016, Arginine silicate and mental tests)

  • L-citrulline: HCl + malate, at most

    The label holds 3.3% of the low study amount
    Per capsule on the HoneyPezil label200 mg
    Up to 6,000 mg a day for 4 weeks in short NIH-listed safety studies6,000 mg

    Both bars use one scale. The label amount is printed on the Supplement Facts panel. (NIH ODS, Exercise and athletic performance supplements)

  • Beta-alanine

    The label holds 1% of the low study amount
    Per capsule on the HoneyPezil label40 mg
    4,000 to 6,000 mg a day in the sports-nutrition position stand4,000-6,000 mg

    Both bars use one scale. The label amount is printed on the Supplement Facts panel. (Trexler 2015, ISSN position stand: Beta-alanine)

Gold bars: the amount printed on the HoneyPezil label for one capsule (forms of the same amino acid added together). Dark bars: the amount used in the study or guidance we found. A studied dose says what was tested, not what works for you, and no study tested HoneyPezil.

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Safety04

Who should be careful with arginine and citrulline?

People on nitrates, erection medicines, blood pressure medicine, blood thinners or diabetes medicine should ask a doctor or pharmacist first.

Blood pressure can fall too far when nitrates and erection medicines are combined (StatPearls, Nitrates and erection medicines). Arginine adds to that concern (Mayo Clinic, L-arginine). Mayo Clinic does not recommend arginine after a heart attack, and a trial in 153 people stopped after 6 deaths in the arginine group (Schulman 2006, Arginine after a heart attack).

Keep taking prescribed medicine exactly as directed. Chest pain or sudden confusion needs 911 (CDC, Heart attack signs). Memory trouble that lasts deserves a doctor first (Mayo Clinic, Memory loss: when to seek help).

FAQ05

HoneyPezil questions people ask

Is HoneyPezil a nitric oxide booster?

The label does not use that phrase. It lists arginine and citrulline lines, which sellers call precursors. We found no study that tested HoneyPezil.

How much arginine is in HoneyPezil?

At most 400 mg per capsule: 200 mg base plus 200 mg from the AKG line. The label does not split the AKG line.

Does citrulline lower blood pressure?

Analyses disagree, and they used grams a day. No study tested 100 mg. Ask your doctor if you take blood pressure medicine.

Who wrote this06

Written and reviewed by

Written byThe HoneyPezil label deskIhoneypezil, U.S. stocking partner for HoneyPezil

Pages built from the label, the brand panels and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Neelum Aggarwal, MD, PhysicianRole: Medical reviewerReview date: October 31, 2026

Last updated . Read our editorial standards and how we check reviews. This website is the information site for a U.S. stocking partner for HoneyPezil. It is not the manufacturer or the distributor named on the label. We earn money when you buy through our order links.

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Check your medicines first, especially nitrates, erection medicines and blood pressure medicine, then pick a pack. One bottle is 30 days at 1 capsule a day; 3 bottles cover 90 days and 6 cover 180. A supplement does not replace a doctor's visit for memory trouble that lasts.

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