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Are memory supplements safe? The FDA's role, doses and medicines
Are memory supplements safe? It depends on the ingredient, the dose and your medicines. The FDA does not approve supplements before sale, and the maker is responsible for safety. HoneyPezil prints at most 400 mg of arginine ingredients per capsule, and arginine can interact with nitrates, erection medicines and blood pressure medicine.
- FormatCapsules, 30 per bottle
- Label serving1 capsule a day
- Guarantee60-day money-back guarantee
Written by the HoneyPezil label deskUpdated · 4 min read
The FDA01
What is the FDA's role with memory supplements?
The FDA does not have the authority to approve dietary supplements before they are sold (FDA, Q&A on Dietary Supplements).
The maker is responsible for safety and truthful labeling (FDA, Dietary Supplements). Makers must follow good manufacturing practice rules, but a rule on paper is not proof for a given bottle (21 CFR Part 111 (eCFR)).
If a supplement upsets you, you can report the reaction to the FDA through MedWatch (FDA, MedWatch). HoneyPezil's label carries the standard FDA statement, and no lab report is published for it.
Doses02
Are the doses in memory supplements safe?
Dose safety is judged one ingredient at a time, and the HoneyPezil amounts sit below the studied amounts.
The bars compare each label amount with a reference marker on a log scale. Studies of citrulline used up to 6,000 mg a day for 4 weeks in short safety studies, against at most 200 mg per capsule (NIH ODS, Exercise and athletic performance supplements). Beta-alanine tingling can start around 800 mg in a single dose, against 40 mg here.
7 linesone capsule a day, 30 a bottle; every amount printed, no proprietary blend
- L-arginine: base + AKG (at most)400 mg · ref 1,500
- L-citrulline: HCl + malate (at most)200 mg · ref 6,000
- Beta-alanine40 mg · ref 4,000
- Niacin7.5 mg · ref 16
- Calcium18 mg · ref 1,300
Per capsule on the labelAmount a study or an authority used or set (low end)
Log scale: each step to the right is ten times more. A marker far to the right of the bar means the label holds much less than that reference. (Kalman 2016, Arginine silicate and mental tests) (NIH ODS, Exercise and athletic performance supplements) (Trexler 2015, ISSN position stand: Beta-alanine) (NIH ODS, Niacin) (NIH ODS, Calcium)
Niacin at 7.5 mg NE is about 21% of the 35 mg upper limit for supplements (NIH ODS, Niacin). Low amounts do not make a product safe for everyone, so the medicine check still applies.
Medicines03
Which medicines make a memory supplement unsafe to combine?
Nitrates, erection medicines, blood pressure medicine, blood thinners, diabetes medicine and potassium-sparing diuretics are the ones to ask about for arginine (Mayo Clinic, L-arginine).
| If you take | Ask about |
|---|---|
| Nitrates or sildenafil-type medicine | Arginine: blood pressure may drop too low |
| Blood thinner | Arginine: bleeding risk |
| Diabetes medicine | Arginine: blood sugar may fall |
| Isoniazid or pyrazinamide | Niacin (NIH ODS, Niacin) |
Keep taking prescribed medicine exactly as directed. Mayo Clinic does not recommend arginine after a recent heart attack.
HoneyPezil: 2, 3 or 6 bottles30 capsules a bottle · 30 days at 1 a day · 60-day money-back guarantee
See packsWho should ask04
Who should ask a doctor before taking a memory supplement?
Pregnant or nursing mothers, children under 18 and anyone with a known medical condition should consult a physician, as the HoneyPezil label says.
Anyone on regular medicine should ask a pharmacist too, and spell the name: H-o-n-e-y-P-e-z-i-l. Look-alike names are a known cause of mix-ups (FDA, Proprietary names guidance). HoneyPezil is a dietary supplement, not a drug.
Chest pain or stroke signs mean 911. Memory trouble that lasts deserves a doctor first. See the side effects page.
FAQ05
HoneyPezil questions people ask
Does the FDA test memory supplements before they are sold?
No. The FDA does not approve supplements before sale. After sale it can act on safety problems, and you can report reactions to MedWatch.
Is a lower dose always safer?
Not always. Medicine interactions and personal conditions matter at any dose. Ask a pharmacist, mainly if you take nitrates or blood pressure medicine.
What are the common side effects of arginine?
Mayo Clinic lists nausea, abdominal pain, diarrhea, bloating, gout, headache, allergic reactions and worsened asthma. Stop if you feel unwell and tell your doctor.
Who wrote this06
Written and reviewed by
Pages built from the label, the brand panels and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is the information site for a U.S. stocking partner for HoneyPezil. It is not the manufacturer or the distributor named on the label. We earn money when you buy through our order links.
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Ready to try HoneyPezil?
Check your medicines first, especially nitrates, erection medicines and blood pressure medicine, then pick a pack. One bottle is 30 days at 1 capsule a day; 3 bottles cover 90 days and 6 cover 180. A supplement does not replace a doctor's visit for memory trouble that lasts.
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